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The immune system and blood regeneration count on hematopoietic stem cells (HSCs), that happen to be critical due to their versatility in cell differentiation into many blood cell types45. The utilization of these cells in bone marrow transplants signifies a cornerstone in hematological therapies, giving a curative method for conditions like leukem

ninety two.Benveniste P, Serra P, Dervovic D, et al. Notch signals are needed for in vitro but not in vivo routine maintenance of human hematopoietic stem cells and delay the looks of multipotent progenitors. BloodRegardless of the immense possible, stem cell therapy faces challenges for example immune rejection, tumorigenesis, along with the speci